devil deal, pink, brown, face, spots, Can be placed next to a pit and exploded to make a bridge, Can be placed over a broken red poop to overwrite it, causing it to no longer regenerate, Counts as 1 of 3 poop items needed towards the Oh Crap transformation, * item room, treasure room, item room pool, starting, turd, brown, Drops a large bomb below the player which does 185 damage, Compatible with bomb modifiers, such as Glitter Bombs, Sticky Bombs etc, Has a chance to drop from the Wrath miniboss fight, REPENTANCE - Damage buffed from 110 to 185, Item Pool: Item Room, Wrath Miniboss, Bomb Beggar, * mr boom, boss rush pool, boss rush room, item room, treasure room, item room pool, bomb beggar, face, smile, grey, gray, Each tear is equal to your damage stat + 25 flat damage, The tears spawned from Tammy's Head retain tear effects of Isaac's tears, such as poison or homing, * golden chest pool, gold chest pool, dead, cat, white, yellow, tammys head, tammy head, When used, freezes all enemies in the current room for about 4 seconds, Item Pool: Item Room, Challenge Room, Mom's Chest, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, When used, replaces all pedestal items in the current room with another random item. The finger deals 10% of your normal damage to all enemies in the same direction that the finger is pointing, The finger will also deal damage to entities such as fires and poops, Applies on-hit status effects such as the burning debuff from Fire Mind, Spawns guppy flies if you have the Guppy transformation, Isaac gains a shadow familiar that will follow Isaac's movement pattern delayed by 1 second and deal 5 contact damage to enemies per tick, Shade is absorbed by Isaac after dealing 666 damage. This gives Isaac a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Samson, Activates the Mega Blast item effect, which gives you a giant laser that deals x5 your tear damage per tick to anything in its path and pushing Isaac back by the force, The effect lasts for 8 seconds but does persist between rooms, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Azazel, When used this kills Isaac and revives him with 1/2 a red heart. Doesn't include Curse Room doors or spiked rocks, Tears can be controlled mid-flight using the directional keys, In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him, Fully heals all your red heart containers, Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it, The visual effect is similar to the effect given to tears by the GodHead item, The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac, In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect, The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades, Upon taking damage, you have a chance to dislodge the spider from your face. . This means the trinket does nothing if your active item isn't fully charged, Single-use active items are consumed as normal, Doors can be opened without using up a key, However, when entering the door you are taken to a blue womb room with enemies to defeat. Dead Bird) then Box of Friends will cause it to spawn but won't create duplicates, This can be used multiple times in the same room to generate more familiars, meaning you can get a level 4 meatboy or bandage girl by using this item 3 times in the same room, If used when you have no familiars, it will give you a Demon Baby temporarily, UNLOCK: Unlock this item by beating Greed Mode with Lilith, Isaac wears a dunce hat and fires 2 tears at once diagonally, similar to the R U A WIZARD pill tear pattern, * Item Room, Greed Mode Item Room, dunce cap, white, hat, cone, Replaces Isaac's tears with nails, which have increased knockback, The increased knockback will also affect Brimstone, which usually has no knockback at all, Gives you a familiar demon incubus that follows you and shoots tears that scale with your own tears in terms of damage, stats and also effects, It will mimic any tear effects you currently have and also copy your current stats, meaning it will fire with the same damage, fire rate and range, Incubus' damage is reduced by 25% when playing as characters other than Lilith, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Lilith, Item Pool: Devil Room, Greed Mode Devil Room, A familiar blue head that will follow Isaac and fire tears copying his tear damage and effects, This familiar is very similar to Incubus, however it only copies damage and is not affected by tears or range upgrades, UNLOCK: Unlock this item by beating Blue Womb (Hush) with ??? mario, cartridge, nes, grey, gray, orange, When used, rerolls each item you currently own into another item room pool item and any pedestal items and pickups in the room, Has the combined uses of the D4, D6 and D20, REPENTANCE - Full run reroll effects (such as D4) are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by beating Boss Rush with The Lost, * item room, treasure room, item room pool, deathstar, death star, dice pip, white, circle, sphere, When used, the D4 re-rolls each item you currently have into another random item from the same item pool, If you have an item with no room pool (e.g. paper, roll, white, All of Isaac's bombs now having a homing effect when placed on the floor, * boss rush pool, boss rush room, item room, treasure room, item room pool, bomb beggar, dead, Aries, Cancer, Capricorn, Leo etc.). In the burst of tears is a kidney stone which deals a lot of damage, REPENTANCE - Kidney Stone is no longer a speed downgrade, UNLOCK: Unlock this item by beating Challenge #29 (Onan's Streak), Upon use, fires a huge Mega Satan laser for 15 seconds, dealing your tear damage * 5 per tick to anything in its path and pushing Isaac back by the force, The laser persists for the entire 15 seconds even between rooms and floors, This item appears in the Devil Room but is weighted to be about 5 times rarer than all other devil room items, UNLOCK: Unlock this item by beating Mega Satan with every character, *, red, grey, gray, brown, black, red, eyes, A crown appears above your head and while at exactly 1 full red heart of health, you gain a +1.5 Range Up, +2.0 Tears Up and +0.20 Shot Speed Up, Any time your health changes to be not exactly 1 red heart you lose the effect. ), Doesn't show the location of Secret or Super Secret rooms, Room icons will not show if a Curse of the Lost is in effect on the current floor, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Heals one red heart container when picked up, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow. This may cause you to skip floors where you left a trinket to spawn a Cracked Key. ?, Satan and The Lamb as Tainted Jacob, Gives you a familiar that follows Isaac's exact movements (similar to how Jacob & Esau work) and shoots spectral tears, Similar to Jacob and Esau, positions can be altered by running it into objects, or holding the drop button (Ctrl on Steam version), When you place a bomb, the Found Soul will drop one too, If it takes any damage, it will die and not respawn until the next floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Jacob, Everytime you use your active item, you have a chance to activate another random active item, Glowing Hourglass effect is blocked from this item, UNLOCK: Unlock this trinket by defeating Isaac, ?? ?, as they cannot gain red heart containers (except for counting towards the Spun transformation), REPENTANCE - Adrenaline now grants an increasingly higher damage bonus the more empty heart containers Isaac has, * Adderline, pink, syringe, needle, injection, Isaac gains electric tears, which fire 1-2 sparks of electricty in random directions upon hitting any object or enemy, The electricity will chain between nearby enemies, The electricty deals half of your normal tear damage, Tear effects will still apply to your electricty sparks in a lot of cases. Notes Brimstone is a special item. grey, gray, blue, moms eyeshadow, Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time, The chance to concuss enemies is affected by your luck stat and at +27 Luck it will activate every time, * item room, treasure room, item room pool, grey, gray, silver, ingot. shop item pool, x, paper, Makes all of Isaac's familiars stronger and bigger, Causes most familiars to deal double damage, Has no effect on most familiars that scale with Isaac's tear damage, * key master pool, key beggar pool, key judgement pool, shop room pool, shop item pool, red, heart, the lost item pool, A familiar that follows Isaac and fires black tar tears, which slow enemy movement and projectile speed for a few seconds, Little Gish fires tears at a rate of 1 tear per second, A Guaranteed drop from the Gish boss fight, UNLOCK: Unlock this item by beating the Depths 20 times and killing the Gish boss, * item room, treasure room, item room pool, grey, gray, yellow, eyes, face, A familiar that follows Isaac and fires homing tears that deal 3.5 damage each, Has a high chance to drop from the Steven boss fight, Little Steven fires tears at a rate of 1 tear per second with a slightly longer range than other familiars, UNLOCK: Unlock this item by killing the Steven boss for the first time, * boss room pool, boss room item, item room, treasure room, item room pool, black, baby, white, eyes, UNLOCK: Unlock this item by killing Mom (Mom's Foot or Mom's Heart) using The Bible, * angel room pool, god room pool, angel room item, boss room pool, boss room item, item room, The only way to remove broken hearts is by donating to a Confessional Machine, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Jacob & Esau, Holding the fire button charges up a light beam attack similar to Brimstone, The light beam deals damage equal to your current tear damage per tick to any enemies touching it, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Bethany, When picked up, this item gives you a stat increase, based on which is currently the lowest. Will take red hearts first before any other, Eve starts with this item after donating 439 coins to the Greed Donation Machine, UNLOCK: Unlock this item by beating Satan with Eve, Item Pool: Item Room, Curse Room, Demon Beggar, * devil pool, devil room pool, devil deal, the lost item pool, starting, silver, grey, gray, Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor, UNLOCK: Unlock this item by beating Satan with Blue Baby, Item Pool: Item Room, Secret Room, Devil Room, Demon Beggar, * secret room pool, item room, treasure room, item room pool, pill, tablet, drug, white, REPENTANCE - Brown Nugget flies now have faster shot speed, and their damage has been increased to 3.5 (from 2). Starts at +3.6 damage and goes to 0 after 30 seconds, While this temporary damage boost is active, each enemy you kill increases your damage slightly, allowing you to quickly kill multiple enemies and chain the effect for longer, This item also gives a -0.03 Speed Down for every food item held. Doesn't apply to progress items like The Polaroid, When you pick up an item that increases your maximum HP, you gain 2 permanent stat increases, and a temporary damage boost that slowly goes down over time. The Binding of Isaac was released in 2011 and has undergone a complete re-release since, along with four expansions. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost', If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway, UNLOCK: Unlock this item by beating the Chest with Eden, 80% of heart drops are replaced with keys, Hearts turn into black hearts where possible. Can only be accessed via the Red Key, Crystal Key or Cracked Key. purple, pink, circle, guppys collar, All of Isaac's tears now have a shield, allowing them to block an enemy projectile, If a tear blocks something, both Isaac's and the enemies tears are destroyed, * secret room pool, item room, treasure room, item room pool, white, lump, oval, When Isaac takes damage, he will start to leave a trail of blood creep behind him as he walks for the current room. purple, pink, mask, face, Puts a shield in front of Isaac which blocks projectiles, The shield will rotate based on the direction in which Isaac is firing tears, * angel room pool, god room pool, angel room item, blue, silver, metal, Gives Isaac a laser that will fire at random intervals in addition to your normal tears, Each laser does damage equal to your current tear damage, The laser will occasionally fire with one of these effects: Hook Worm, Spoon Bender, Tiny Planet, Mysterious Liquid, Rubber Cement, Luck has no effect on the rate at which Tech.5 fires and does not scale with items that increase your tears stat, UNLOCK: Unlock this item by beating Challenge #18 (The Host), * technology.5, tech 5, item room, treasure room, item room pool, white, red, eye, robot, Isaac now shoots two tears at once, but dealing -20% damage each, Unlike the Inner Eye and Mutant Spider items, this double shot item does not give a tears down, * 20 20, 2020, item room, treasure room, item room pool, black glasses, spectacles, Reveals the locations of the secret and super secret room for the current floor and all future floors, UNLOCK: Unlock this item by donating 10 pennies to the Shop, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, This means you can leave rooms before defeating the enemies inside, Doesn't open locked doors, or the door that leads to the Boss Room, This item causes nearby enemies to be affected by the charm effect, causing them to attack other nearby enemies, The charm effect will wear off very quicky when enemies move away from Isaac, This item causes your tears to become rocks, which have increased knockback and can break other rocks and objects. Spawns coins as The Keeper, I can see forever - Opens secret room and super secret room entrances on the current floor, I found pills - Changes the appearance of Isaac's face for the current room (Cosmetic change only), Lemon Party - Spawns a large yellow pool on the floor around you, damaging enemies which walk in it, Paralysis - Prevents you from moving for a short while, Pheromones - Applies the charm effect to all enemies in the room for a short while, Puberty - Causes Isaac to grow hair for the rest of the run. They modify Isaac's Attributes, grant or modify Tear Effects, and much more. Abel, UNLOCK: Unlock this trinket by defeating Isaac, ?? Stat Up becomes Stat Down), Any 'Stat down' pills you take give you a permanent +0.6 Damage Up (Horse pills +1.2), Most other pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ?? ?, Soul of the Lost, 4 rooms: Rune of Ehwaz, Rune of Perthro, Black Rune, Soul of Isaac, Soul of Eve, Soul of Eden, Soul of the Forgotten, Soul of Jacob and Esau, 6 rooms: Rune of Dagaz, Soul of Samson, Soul of Azazel, Soul of Apollyon, Soul of Bethany, 12 rooms: Rune of Jera, Soul of Lilith, Soul of the Keeper, Tears have a chance to fire a fungus tear that sticks to enemies. If you haven't unlocked Holy Mantle for The Lost yet, you won't gain the effect after touching a white fire so be careful! UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. After killing a 15 enemies, Blood Puppy transforms into an aggressive version that will also attack Isaac by charging at him. Doing this will cause this Golden Battery to reappear somewhere else on the floor, UNLOCK: Unlock this by defeating Mega Satan as Tainted Forgotten, Spawns similar to regular troll bombs and cannot be picked up, However, they will explode forever instead of disappearing, The Safety Scissors trinket will turn this into a gold bomb, When picked up, will respawn again at a random location in the room, Every time you pick up a golden penny it has a 5% chance to disappear completely, UNLOCK: Unlock this by defeating Mega Satan as Tainted Keeper, Once picked up, the gold heart will drop money on the floor the next time Isaac loses a heart, UNLOCK: Unlock this item by beating challenge #21 (XXXXXXXXL), Takes three hits to deplete and can be refilled with red hearts, but disappears forever when depleted, UNLOCK: Unlock this item by unlocking the Forgotten character. spray, brown, white, yellow, moms purfume, Tears can now be charged and released in a shotgun style effect, much like Monstro's main attack, Partial charging does nothing - must be fully charged to use, * item room, treasure room, item room pool, pink, body part, monstros lung, On pickup Abaddon converts all your heart containers to black hearts, then gives you +2 more black hearts, Tears now have a chance to induce the fear effect, causing enemies to run away from Isaac for a short period, REPENTANCE - No longer kills Keeper when picked up, just reduces coin health to 1, UNLOCK: Unlock this item by beating the Chest with Azazel, * devil pool, devil room pool, devil deal, red devil sign, abandon, abadon, pentagram, Isaac leaves a trail of tar behind him which will slow down enemies that walk over it, Tears have a chance to slow enemies and their projectiles for a short period of time, The chance to slow enemies can improve based on your luck stat and will always slow enemies at +18 Luck, * item room, treasure room, item room pool, black, grey, gray, The Stop Watch applies a permanent but slight slowing effect to all enemies and their projectiles, The slowing effect has a reduced effect against Brimstone lasers fired by enemies, REPENTANCE - Stop Watch now slows down all enemies in the game once again, but the slow effect is much less drastic.
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